市场价:元价格:元

  • 中文名称:tertButyldimethylsilyl chloride
  • CAS RN:18162-48-6
  • EINECS号:242-042-4
  • 分 子 式:C6H15ClSi
  • 分 子 量:150.7218
  • 分子式:
Character description

White or off white crystal

Physical parameter editing

Melting point: 86-89 ℃ (lit.)

Boiling point: 125 ℃ (lit.)

Flash point: 53 C

Quality standard

Purity: ≥ 98% (HPLC)

Loss on drying: ≤ 0.5%

Heavy metal: ≤ 20ppm

Safety terminology

S16keep away from sources of ignition.

Keep away from fire.

S25avoid contact with eyes.

Avoid eye contact.

S36 / 37 / 39wear suitable protective clothing, eyes and eye / face protection.

Wear appropriate protective clothing, gloves and goggles or masks.

S45in case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

In the event of an accident or discomfort, seek medical attention immediately (show label if possible).

Risk terminology

R10flammable.

Flammable.

R34 causes burns.

Cause burns.

Usage description

Multi purpose amines, amides, especially alcohols, and other protective reagents. Under the protection of t-buph2si-based ethanol, it can be selectively removed; it is used to prepare N-oxide of isoxazoline from α - bromonitroalkane; it is an effective derivative reagent for preparation and analysis purposes, and it can selectively remove tbdms ethers.

Storage and transportation

Keep in a cool and dry place

Hazard statement

Hazard Code: C

Hazard class: 10-34

Safety level: 16-26-36 / 37 / 39-45

UN No.: un2925

Physical and chemical properties

Density 0.81g/cm ^ 3 melting point 85-91 ° C boiling point 125 ° C flash point 22 ° C

Product use

[application 1] auxiliary raw materials for the synthesis of prostaglandins, some antibiotics, lipid lowering drugs lovastatin and simvastatin

[application 2] used as pharmaceutical intermediate, organic synthesis and hydroxyl protection agent in organic synthesis

[application 3] silanization agent. In organic synthesis, it is used as hydroxyl protecting agent and derivatization agent for analysis and preparation. Protect tertiary alcohols. It reacts with alcohols to form silicon ether. The conformation of cholesterol derivatives was determined. Prostaglandins, adjuvants of some antibiotics, lipid lowering drugs lovastatin and simvastatin

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